Fistful of Dollars (Italian: Per un pugno di dollari) is a 1964 Italian Spaghetti Western film directed by Sergio Leone and starring Clint Eastwood alongside Gian Maria Volonté, Marianne Koch, Wolfgang Lukschy, Sieghardt Rupp, José Calvo, Antonio Prieto, and Joseph Egger. Released in Italy in 1964 then in the United States in 1967, it initiated the popularity of the Spaghetti Western film genre. It was followed by For a Few Dollars More (1965) and The Good, the Bad and the Ugly (1966), also starring Eastwood. Collectively, the films are commonly known as the "Dollars Trilogy" or "The Man With No Name Trilogy". This film is an unofficial remake of the Akira Kurosawa film Yojimbo (1961), which itself drew inspiration from earlier Westerns. In the United States, the United Artists publicity campaign referred to Eastwood's character in all three films as the "Man with No Name".

As one of the first Spaghetti Westerns to be released in the United States, many of the European cast and crew took on American sounding stage names. These included Leone himself ("Bob Robertson"), Gian Maria Volonté ("Johnny Wels"), and composer Ennio Morricone ("Dan Savio").

A Fistful of Dollars was shot in Spain, mostly near Hoyo de Manzanares close to Madrid, but also (like its two sequels) in the Cabo de Gata-Níjar Natural Park in Almería province.

Before this film Clint Eastwood had especially been known from Rawhide. Ty Hardin, at that time well-known for playing the protagonist in the TV show Bronco, who appeared in several other European westerns at about the same time, claimed later on he had as well had an opportunity to get the role which started Clint Eastwood's unique career in cinema.