Major League II is a 1994 sequel to the 1989 film Major League. Major League II stars most of the same cast from the original, including Charlie Sheen, Tom Berenger, and Corbin Bernsen. Absent from this film is Wesley Snipes, who played Willie Mays Hayes in the first film and who by 1994 had become a film star in his own right. Omar Epps took over his role.

Major League II also welcomes some new faces to the team. David Keith plays Jack Parkman, a selfish superstar catcher who is looking to replace the aging Jake Taylor (Tom Berenger) as the starter. Takaaki Ishibashi of Japanese comedic duo Tunnels is a new outfielder, Isuro "Kamikazi" Tanaka, who helps excite the team. Eric Bruskotter is the rookie catcher Rube Baker who is getting used to the MLB life.

Randy Quaid makes a cameo appearance in the film as a fair weather fan.