I'm going to start compiling a list. Talking with Lecter in the Stallone thread made me want to do this. There isn't too much information for me to go on, outside of BOM. So obviously it'll most stick to post 1980, unless there is direct information.

Going to put the overall list here.

Tom Cruise- 21
Bruce Willis- 17
Harrison Ford- 17
Eddie Murphy- 16
Sylvester Stallone- 16
Robin Williams- 15
Morgan Freeman- 15
Tom Hanks- 15
Jim Carrey- 15
Nic Cage- 15
Arnold Schwarzenegger- 14
Tommy Lee Jones- 13
Liam Neeson- 13
Mel Gibson- 13
Will Smith- 13
Mark Walhberg- 12
Denzel Washington- 12
Julia Roberts- 12
John Travolta- 11
Sigourney Weaver- 11
Matt Damon- 10
Keanu Reeves- 10
Nicole Kidman-10
Cameron Diaz- 10
Bill Murray- 10
Michael Douglas- 10
George Clooney-10
Johnny Depp- 10
Sandra Bullock- 9
Helena Bohnam Carter- 9
Angelina Jolie- 9
Robert Downey Jr.- 8
Clint Eastwood- 8 (That we know of)
Wesley Snipes- 8
Ben Affleck- 8
Jodie Foster-8
Meryl Streep- 6
Kevin Costner- 6
Steven Seagal- 6
Leonardo DiCaprio- 5
Jeff Bridges- 5
Richard Gere- 5
Kurt Russell- 4
Russell Crowe- 4

You were conversing with me in the Stallone thread, sir.

Starting off with Mel Gibson.

Lethal Weapon
Lethal Weapon 2
Bird on a Wire
Lethal Weapon 3
Maverick
Pocahantas
Ransom
Conspiracy Theory
Lethal Weapon 4
Payback
What Women Want
We Were Soldiers
Signs

Mel Gibson Total: 13 from 1987 to 2002
Highest opening: Signs- 60.1 million
Top 3 openings Adjusted: Signs- 83 million, Lethal Weapon 3- 64 million, Ransom- 62 million
Note: He also has 2 director titles that opened to #1: Passion of the Christ and Apocalypto

Jim Carrey:

Ace Ventura: Pet Detective: 12 million (February 1994)
The Mask: 23 million (July 1994)
Dumb and Dumber: 16 million (December 1994)
Batman Forever: 52 million (June 1995)
Ace Ventura: When Nature Calls: 37 million (November 1995)
The Cable Guy: 19 million (June 1996)
Liar Liar: 31 million (March 1997)
The Truman Show: 31 million (June 1998)
Me, Myself & Irene: 24 million (June 2000)
How the Grinch Stole Christmas: 55 million (November 2000)
Bruce Almighty: 67 million (May 2003)
Lemony Snicket's A Series of Unfortunate Events: 30 million (December 2004)
Horton Hears a Who!: 45 million (March 2008)
Yes Man: 18 million (December 2008)
A Christmas Carol: 30 million (November 2009)

15 in total from 1994 to 2009.

EDIT: I s'pose the top three adjusted would be -

1. Batman Forever: 97 million
2. Bruce Almighty: 90 million
2. How the Grinch Stole Christmas: 82 million

If you are strictly technical, Gibson's count is 12 since Pocahontas hit number one upon expansion, but opened in limited release.

No Lie, I was doing Jim Carrey before I even looked at you. Can you also update it to the top 3 adjusted please David?

Shit, he found out our secret!!

I'm sticking with wide releases, as Pocahontas opening was extremely impressive limited as well, but it still debuted wide following week. That was more there version of previews back then. Also trying to stick away from appearances, starring roles, including starring animated roles.

Arnold Schwarzenegger:

Conan The Barbarian- 9.6 million (82)
The Terminator- 4 million (84)
Commando- 7 million (85)
Predator- 12 million (87)
The Running Man- 8 million (87)
Twins- 11.2 million (88)
Total Recall- 25.5 million (90)
Terminator 2: Judgement Day- 31.8 million (91)
True Lies- 25.9 million (94)
Eraser- 24.6 million (96)
Batman and Robin- 42.9 million (97)
Collateral Damage- 15 million (02)
Terminator 3: Rise of the Machines- 44 million (03)
Expendables 2: 28.6 million (12)

Arnold total: 14 from 1982-2012
Highest opening: Terminator 3
Top 3 Adjusted: Batman and Robin (75 million) Terminator 2 (61 million) Terminator 3 (59 million)
Note: Expendables seemed like a stretch, but Expendables 2 was a sizable enough role for him.

Michael Douglas

Fatal Attraction- 7.6 million (87)
Black Rain- 9.7 million (89)
War of the Roses- 9.5 million (89)
Basic Instinct- 15 million (92)
Falling Down- 8.7 million (93)
Disclosure- 10 million (94)
The Ghost and the Darkness- 9.2 million (96)
The Game- 14.3 million (97)
Don't Say a word- 17 million (01)
Wall Street: Money Never Sleeps- 19 million (10)

Michael Douglas Total: 10 from 1987-2010
Highest opening: You, Me and Dupree- 21 million
Top 3 Adjusted: Basic Instinct (29 million) A Perfect murder- 28.5 million, You, Me, and Dupree, 26.5 million
Note: He also produced Cookoos Nest, Face off, and Flatliners to #1 openings as well

That's surprisingly low for his biggest opening weekend...

Douglas always had a respected following, and highly paid, but his films always depended more on legs, and were less about action and big budgets. Only 3 crossed 100 million unadjusted. Fatal Attraction's opening only adjusts 16 million, but the total gross adjusts to 320 million.

Nicolas Cage:

Guarding Tess: 7 million (March 1994)
The Rock: 25 million (June 1996)
Con Air: 24 million (June 1997)
Face/Off: 23 million (June 1997)
City of Angels: 15 million (April 1998)
8MM: 14 million (February 1999)
Gone in 60 Seconds: 25 million (June 2000)
National Treasure: 35 million (November 2004)
Ghost Rider: 45 million (February 2007)
National Treasure: Book of Secrets: 44 million (December 2007)
Bangkok Dangerous: 7 million (September 2008)
Knowing: 24 million (March 2009)
G-Force: 31 million (July 2009)
Kick-Ass: 19 million (April 2010)
The Croods: 43 million (March 2013)

15 from 1994 to 2013. 13 if you exclude animated films.

Top three adjusted openings:

1. National Treasure: Book of Secrets: 52 million
2. The Rock: 45.7 million
3. National Treasure: 45.6 million

Eddie Murphy

Beverly Hills cop- 15.2 million (84)
The Golden Child- 11.6 million (86)
Beverly Hills Cop II- 26.3 million (87)
Eddie Murphy Raw- 9 million (87)
Coming to America- 21.4 million (88)
Harlem Nights- 16.1 million (90)
Another 48 Hours- 19.5 million (90)
The Nutty Professor- 25.4 million (96)
Dr. Dolittle- 29 million (98)
Life- 20.4 million (99)
Nutty Professor II: The Klumps- 42.5 million (00)
Shrek- 42 million (01)
Shrek 2- 108 million (04)
Norbit- 34 million (07)
Shrek the Third- 122 million (07)
Shrek Forever After- 70.8 million (10)

Eddie Murphy Total: 16 from 1984-2010
Highest opening: Shrek the Third- 121.6 million
Top 3 Adjusted (Non Shrek): NPII (63.5 million) Beverly Hills Cop II (54 million) Dr. Dolittle (49.8 million)
Note: Obviously Shrek brought him a long way. His first 7 were consecutive #1 hits

Ill help, if theres no problem

Ben Affleck

Armageddon- $36.1M (1998)
Forces of Nature- $13.5M (1999)
Pearl Harbor- $59.1M [$75.2M 4DAY Wknd] (2001)
Changing Lanes- $17.1M (2002)
The Sum of All Fears- $31.2M (2002)
Daredevil- $40.3M (2003)
He's Just Not That Into You- $27.8M (2009)
The Town- $23.8M (2010)

TOTAL: 9 (1998-2010)
Highest Opening: Pearl Harbor- $59.1M [$75.2M 4DAY Wknd]

Dont know why but I expected more from Ben

Wow

Wow!!! Fun Thread. When you say actors does it mean male actors only or can we also do female actors?

You'll have to ask their husbands' permission first.

Lecter is in fun mood today

Fixed.

George Clooney

From Dusk Till Dawn- $10.2M (1996)
The Peacemaker- $12.3M (1997)
Batman and Robin- $42.9M (1997)
The Perfect Storm- $41.3M (2000)
Ocean's Eleven- $38.1M (2001)
Ocean's Twelve- $39.2M (2004)
Ocean's Thirteen- $36.1M (2007)
Burn After Reading- $19.1M (2008)
The American- $13.2M (2010)
Gravity- $55.8M (2013)

TOTAL: 10 (1996-2013)
Highest Opening: Gravity- $55.8M (2013)

Samuel L. Jackson has definitely got this.

Just out of curiosity, I went through Robert Redford's career. Unfortunately, only a total gross is available for many of his most iconic films, including All the President's Men, The Sting, and The Way We Were. But he has opened at number one four times since 1984:

The Natural: 5 million (May 1984) - adjusts to 12 million
Sneakers: 10 million (September 1992) - adjusts to 19 million
Indecent Proposal: 18 million (April 1993) - adjusts to 35 million
Up Close & Personal: 11 million (March 1996) - adjusts to 20 million

Out of Africa reached number one later in its run, but opened at number four.

Stallone - 18

1. The Expendables 2
2. The Expendables
3. Driven
4. Spy Kids 3D
5. Rambo: First Blood Part II
6. Rocky IV
7. Rocky II
8. Cliffhanger
9. Demolition Man
10. The Specialist
11. Oscar
12. Cop Land
13. Cobra
14. First Blood
15. Rocky III
16. Antz
17. Staying Alive
18. Rocky

Denzel Washington:

The Pelican Brief: 16 million (December 1993)
Philadelphia: 13 million (nationwide expansion in January 1994)
Crimson Tide: 18 million (May 1995)
He Got Game: 7 million (May 1998)
The Bone Collector: 16 million (November 1999)
Remember the Titans: 20 million (September 2000)
Training Day: 22 million (October 2001)
John Q: 20 million (February 2002)
Man on Fire: 22 million (April 2004)
Inside Man: 28 million (March 2006)
American Gangster: 43 million (November 2007)
Safe House: 40 million (February 2012)
2 Guns: 27 million (August 2013)

13 since 1993.