Osmosis Jones is a 2001 American live-action animated buddy cop comedy film written by Marc Hyman. Combining live-action sequences directed by the Farrelly brothers and animation directed by Piet Kroon and Tom Sito, the film stars the voices of Chris Rock, Laurence Fishburne, David Hyde Pierce, Brandy Norwood, and William Shatner, alongside Molly Shannon, Chris Elliott, and Bill Murray in live-action roles. It follows the titular character, an anthropomorphic white blood cell, as he teams up with a cold pill to protect his unhealthy human host from a deadly virus he unintentionally contracted.