Santa Sangre ("Saint Blood") is a 1989 Mexican-Italian surrealist horror film directed by Alejandro Jodorowsky and written by Jodorowsky along with Claudio Argento and Roberto Leoni. Divided into both a flashback and a flashforward, the film, which is set in Mexico, tells the story of Fenix (Axel Jodorowsky), a boy who grew up in a circus, and his life through both adolescence and early adulthood. Whilst still a child, he witnesses his mother Concha (Blanca Guerra), who is devoted to an armless saint, have her own arms cut off by her enraged husband, and being so shocked by this, he is subsequently institutionalised in a mental sanitorium. Eventually leaving the facility as a man, he becomes his mother's servant, literally acting as her arms, and is forced to commit the murders that she commands.

It was screened in the Un Certain Regard section at the 1989 Cannes Film Festival, and generally was critically well received, eventually being ranked 476th on Empire magazine's 2008 list of the 500 greatest movies of all time. Like many of Jodorowsky's films, it has since become a cult film. In the United States, it was originally rated NC-17 for "several scenes of extremely explicit violence". However, an edited version was released with an R rating for "bizarre, graphic violence and sensuality, and for drug content."