Madea's Family Reunion is a 2006 comedy-drama film adaptation of the stage production of the same name written by Tyler Perry and sequel to Diary of a Mad Black Woman. It was written and directed by Perry and features him playing several characters, including Mabel "Madea" Simmons. It was released on February 24, 2006, nearly one year following its predecessor, Diary of a Mad Black Woman. The independent film was produced by Lionsgate.

While planning her family reunion, the pistol-packing grandma, Mabel "Madea" Simmons, must contend with the other dramas on her plate, including the runaway who has been placed under her care, and her troubled nieces, half-sisters Lisa and Vanessa.